May 6, 2025
Episode 16

How Human-Centered AI Actually Gets Built

Fei-Fei Li
Fei-Fei Li
How Human-Centered AI Actually Gets Built

Fei-Fei Li—co-director of Stanford’s Human-Centered AI Institute and one of the most respected voices in the field—reflects on AI’s evolution from the early days of ImageNet to the rise of foundation models. She explains why spatial intelligence may be the next major shift, how human-centered design applies in practice, and why AI should be understood as a civilizational technology—one that shapes individuals, communities, and society at large.

Fei-Fei Li—co-director of Stanford’s Human-Centered AI Institute and one of the most respected voices in the field—reflects on AI’s evolution from the early days of ImageNet to the rise of foundation models. She explains why spatial intelligence may be the next major shift, how human-centered design applies in practice, and why AI should be understood as a civilizational technology—one that shapes individuals, communities, and society at large.

Guest

Fei-Fei Li

Fei-Fei Li

Sequoia Professor in the Computer Science Department at Stanford University, and a Founding Co-Director of Stanford’s Human-Centered AI Institute at Stanford University

Key Takeaways

AI is a civilizational technology.

Fei-Fei emphasizes that AI isn’t just a tool—it’s reshaping geopolitics, labor markets, and the social fabric. The stakes aren’t technical; they’re societal.

Human-centered AI starts with design, not merely technology

From smart sensors in elder care to creator tools, Fei-Fei shows how values like dignity, privacy, and agency must be embedded from the start—not patched in later.

Curiosity is the original North Star.

Tracing her path from physics to AI, Fei-Fei highlights how staying grounded in big questions—not trends—has guided her work across research, teaching, and now entrepreneurship.

Spatial intelligence is the next frontier.

Beyond language models, she argues the future lies in AI that understands and interacts with 3D space—powering new modes of creation, robotics, and real-world interfaces.

World models unlock new forms of interaction.

Flat images lack depth and structure. Fei-Fei explains why modeling space—and building foundational models for it—is key to developing interactive, controllable AI systems.

Institutions matter.

Fei-Fei calls for strong public infrastructure for AI: not just regulation, but investment in education, open research, and an innovation ecosystem that includes universities and entrepreneurs—not just incumbents.

Science, not science fiction.

Policymaking must be grounded in evidence, not hype. Fei-Fei critiques extinction rhetoric and calls for pragmatic, domain-specific regulation focused on real harms and real benefits.

AI will transform every discipline.

From climate modeling to education to public services, she sees AI as a general-purpose tool for discovery—if deployed with care, expertise, and shared intent.

You can read the full transcript here.

Timestamps

00:00 Introduction to AI as a Civilizational Technology 

00:59 Interview with Fei-Fei Li: A Journey Through AI 

03:18 Fei-Fei Li's Pivotal Moments in AI 

12:24 Human-Centered AI: Principles and Applications 

24:46 The Future of AI: Spatial Intelligence and Beyond 

35:26 Challenges and Opportunities in AI Policy 

46:01 Conclusion and Final Thoughts

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